| Item Type | Name |
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Academic Article
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High levels of vascular endothelial growth factor receptor-2 correlate with shortened survival in chronic lymphocytic leukemia.
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Academic Article
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Mechanisms of antileukemic activity of the novel Bcl-2 homology domain-3 mimetic GX15-070 (obatoclax).
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Academic Article
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The JAK kinase inhibitor CP-690,550 suppresses the growth of human polycythemia vera cells carrying the JAK2V617F mutation.
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Academic Article
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The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia.
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Academic Article
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Kit inhibitor APcK110 induces apoptosis and inhibits proliferation of acute myeloid leukemia cells.
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Academic Article
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Circulating endothelial progenitor cells and coronary collaterals in patients with non-ST segment elevation myocardial infarction.
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Academic Article
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Potential role of activated platelets in homing of human endothelial progenitor cells to subendothelial matrix.
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Concept
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Hepatocyte Growth Factor
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Concept
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AraC Transcription Factor
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Concept
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Vascular Endothelial Growth Factor A
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Concept
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Granulocyte Colony-Stimulating Factor
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Concept
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Transforming Growth Factor beta
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Concept
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Receptors, Colony-Stimulating Factor
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Concept
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Leukemia Inhibitory Factor Receptor alpha Subunit
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Concept
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Vascular Endothelial Growth Factor Receptor-1
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Concept
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Insulin-Like Growth Factor I
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Concept
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STAT5 Transcription Factor
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Concept
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Apoptosis Inducing Factor
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Concept
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Core Binding Factor Alpha 2 Subunit
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Concept
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Stem Cell Factor
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Concept
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Receptors, Tumor Necrosis Factor, Type I
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Concept
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Receptors, Granulocyte Colony-Stimulating Factor
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Concept
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Leukemia Inhibitory Factor
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Concept
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STAT3 Transcription Factor
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Concept
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Tumor Necrosis Factor Decoy Receptors
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Concept
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Macrophage Colony-Stimulating Factor
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Concept
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Vascular Endothelial Growth Factor Receptor-2
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Concept
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Receptors, Granulocyte-Macrophage Colony-Stimulating Factor
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Concept
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Receptors, Growth Factor
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Concept
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Factor Analysis, Statistical
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Concept
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Tumor Necrosis Factor-alpha
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Concept
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Receptors, Tumor Necrosis Factor
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Concept
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Receptors, Vascular Endothelial Growth Factor
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Concept
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Fibroblast Growth Factor 2
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Concept
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Transcription Factor RelA
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Concept
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Granulocyte-Macrophage Colony-Stimulating Factor
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Academic Article
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Central role of tumour necrosis factor, GM-CSF, and interleukin 1 in the pathogenesis of juvenile chronic myelogenous leukaemia.
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Academic Article
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Growth factors controlling interleukin-4 action on hematopoietic progenitors.
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Academic Article
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The effect of growth hormone and IGF-I on clonogenic growth of hematopoietic cells in leukemic patients during active disease and during remission--a preliminary report.
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Academic Article
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Leukemia inhibitory factor binds to human breast cancer cells and stimulates their proliferation.
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Academic Article
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Leukemia-inhibitory factor stimulates breast, kidney and prostate cancer cell proliferation by paracrine and autocrine pathways.
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Academic Article
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Z-138: a new mature B-cell acute lymphoblastic leukemia cell line from a patient with transformed chronic lymphocytic leukemia.
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Academic Article
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Serum cytokine levels in infectious mononucleosis at diagnosis and convalescence.
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Academic Article
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Cellular vascular endothelial growth factor is a predictor of outcome in patients with acute myeloid leukemia.
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Academic Article
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Angiogenesis in acute and chronic leukemias and myelodysplastic syndromes.
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Academic Article
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WP1066 disrupts Janus kinase-2 and induces caspase-dependent apoptosis in acute myelogenous leukemia cells.
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Academic Article
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Transformation of human mesenchymal cells and skin fibroblasts into hematopoietic cells.
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Academic Article
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Inhibition of acute myelogenous leukemia blast proliferation by interleukin-1 (IL-1) receptor antagonist and soluble IL-1 receptors.
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Academic Article
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Comparison of in vivo and in vitro effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) in patients with acute myeloid leukemia.
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Academic Article
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Granulocyte-colony stimulating factor, granulocyte-macrophage colony stimulating factor, PIXY-321, stem cell factor, interleukin-3, and interleukin-7: receptor binding and effects on clonogenic proliferation in acute lymphoblastic leukemia.
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Academic Article
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Elevated plasma thrombopoietic activity in patients with metastatic cancer-related thrombocytosis.
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Academic Article
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Cytokines and their antagonists in myeloid disorders.
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Academic Article
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Granulocyte-macrophage colony-stimulating factor as a cause of paraneoplastic leukaemoid reaction in advanced transitional cell carcinoma.
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Academic Article
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Molecular and biologic characterization of a newly established Philadelphia-positive acute lymphoblastic leukemia cell line (Z-33) with an autocrine response to GM-CSF.
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Academic Article
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Identification of human juvenile chronic myelogenous leukemia stem cells capable of initiating the disease in primary and secondary SCID mice.
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Academic Article
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Nuclear factor-kappaB and STAT3 are constitutively active in CD138+ cells derived from multiple myeloma patients, and suppression of these transcription factors leads to apoptosis.
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Academic Article
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Atiprimod blocks phosphorylation of JAK-STAT and inhibits proliferation of acute myeloid leukemia (AML) cells.
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Academic Article
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Soluble syndecan-1 (sCD138) as a prognostic factor independent of mutation status in patients with chronic lymphocytic leukemia.
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Academic Article
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STAT3 is constitutively phosphorylated on serine 727 residues, binds DNA, and activates transcription in CLL cells.
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Academic Article
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STAT-3 activates NF-kappaB in chronic lymphocytic leukemia cells.
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Academic Article
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Final results of the phase II study of rabbit anti-thymocyte globulin, ciclosporin, methylprednisone, and granulocyte colony-stimulating factor in patients with aplastic anaemia and myelodysplastic syndrome.
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Academic Article
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Phase 2 study of the JAK kinase inhibitor ruxolitinib in patients with refractory leukemias, including postmyeloproliferative neoplasm acute myeloid leukemia.
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Academic Article
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Signal transducer and activator of transcription-3 induces microRNA-155 expression in chronic lymphocytic leukemia.
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Academic Article
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The modulatory hematopoietic activities of leukemia inhibitory factor.
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Academic Article
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The effect of granulocyte-macrophage colony-stimulating factor on undifferentiated and mature acute myelogenous leukemia blast progenitors.
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Academic Article
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Suppression of chronic myelogenous leukemia colony growth by interleukin-1 (IL-1) receptor antagonist and soluble IL-1 receptors: a novel application for inhibitors of IL-1 activity.
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Academic Article
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Granulocyte-macrophage colony-stimulating factor and interleukin-3 in combination: a potent and consistent myelodysplastic syndrome bone marrow stimulant in vitro.
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Academic Article
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Human growth hormone and insulin-like growth factor-1 enhance the proliferation of human leukemic blasts.
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Academic Article
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Diamond-Blackfan anemia: promotion of marrow erythropoiesis in vitro by recombinant interleukin-3.
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Academic Article
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Interleukin 4 alters human bone marrow stroma and modulates its interaction with hematopoietic progenitors.
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Academic Article
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Role of suramin as an IL-1 inhibitor in suppression of acute myelogenous leukemia progenitor proliferation.
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Academic Article
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Interruption of autocrine and paracrine growth-stimulatory mechanisms: a new therapeutic strategy for chronic myelogenous leukemia.
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Academic Article
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Lymphotoxin is an autocrine growth factor for Epstein-Barr virus-infected B cell lines.
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Academic Article
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Effect of interleukin-1 beta converting enzyme inhibitor on acute myelogenous leukemia progenitor proliferation.
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Academic Article
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Expression of leukemia inhibitory factor and its receptor in breast cancer: a potential autocrine and paracrine growth regulatory mechanism.
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Academic Article
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Oncostatin M-specific receptor expression and function in regulating cell proliferation of normal and malignant mammary epithelial cells.
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Academic Article
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Thrombopoietin stimulates myelodysplastic syndrome granulocyte-macrophage and erythroid progenitor proliferation.
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Academic Article
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Phenylarsine oxide blocks interleukin-1beta-induced activation of the nuclear transcription factor NF-kappaB, inhibits proliferation, and induces apoptosis of acute myelogenous leukemia cells.
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Academic Article
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Comparison of outcome in acute myelogenous leukemia patients with translocation (8;21) found by standard cytogenetic analysis and patients with AML1/ETO fusion transcript found only by PCR testing.
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Academic Article
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The clinical significance of tumor necrosis factor-alpha plasma level in patients having chronic lymphocytic leukemia.
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Academic Article
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Granulocyte-macrophage colony-stimulating factor (GM-CSF) induces antiapoptotic and proapoptotic signals in acute myeloid leukemia.
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Academic Article
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Atiprimod blocks STAT3 phosphorylation and induces apoptosis in multiple myeloma cells.
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Academic Article
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WP-1034, a novel JAK-STAT inhibitor, with proapoptotic and antileukemic activity in acute myeloid leukemia (AML).
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Academic Article
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Recombinant human granulocyte-colony-stimulating factor-mobilized and apheresis-collected endothelial progenitor cells: a novel blood cell component for therapeutic vasculogenesis.
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Academic Article
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Stat3 activates the receptor tyrosine kinase like orphan receptor-1 gene in chronic lymphocytic leukemia cells.
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Academic Article
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Safety and efficacy of INCB018424, a JAK1 and JAK2 inhibitor, in myelofibrosis.
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Academic Article
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Stimulation of the B-cell receptor activates the JAK2/STAT3 signaling pathway in chronic lymphocytic leukemia cells.
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Academic Article
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Growth requirements for human acute lymphoblastic leukemia cells: refinement of a clonogenic assay.
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Academic Article
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Leukemia inhibitory factor in long-term adherent layer cultures: increased levels of bioactive protein in leukemia and modulation by IL-4, IL-1 beta, and TNF-alpha.
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Academic Article
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Analysis of the effects of tumor necrosis factor inhibitors on human hematopoiesis.
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Academic Article
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Ubiquitous expression of cytokines in diverse leukemias of lymphoid and myeloid lineage.
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Academic Article
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Suppression of chronic myelogenous leukemia colony growth by interleukin-4.
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Academic Article
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Human recombinant interferon-inducible protein-10 inhibits the proliferation of normal and acute myelogenous leukemia progenitors.
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Academic Article
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Flt3 ligand stimulates proliferation and inhibits apoptosis of acute myeloid leukemia cells: regulation of Bcl-2 and Bax.
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Academic Article
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Interleukin-1 increases expression of the LYT-10 (NFkappaB2) proto-oncogene/transcription factor in renal cell carcinoma lines.
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Academic Article
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The anti-angiogenesis agent, AG-013736, has minimal activity in elderly patients with poor prognosis acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).
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Academic Article
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LIF: not just a leukemia inhibitory factor.
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Academic Article
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Role of granulocyte-macrophage colony-stimulating factor in Philadelphia (Ph1)-positive acute lymphoblastic leukemia: studies on two newly established Ph1-positive acute lymphoblastic leukemia cell lines (Z-119 and Z-181).
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Academic Article
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Resveratrol blocks interleukin-1beta-induced activation of the nuclear transcription factor NF-kappaB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells.
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Academic Article
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Expression of constitutively active nuclear-kappa B RelA transcription factor in blasts of acute myeloid leukemia.
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Academic Article
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Cross-talk between chronic lymphocytic leukemia cells and bone marrow endothelial cells: role of signal transducer and activator of transcription 3.
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Academic Article
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Signal transducer and activator of transcription (STAT)-3 regulates microRNA gene expression in chronic lymphocytic leukemia cells.
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Academic Article
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STAT3-activated GM-CSFRa translocates to the nucleus and protects CLL cells from apoptosis.
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Academic Article
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Myeloid neoplasms after breast cancer: "therapy-related" not an independent poor prognostic factor.
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Academic Article
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Aberrant LPL Expression, Driven by STAT3, Mediates Free Fatty Acid Metabolism in CLL Cells.
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Academic Article
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Outcomes of Patients With Chronic Lymphocytic Leukemia and Richter's Transformation After Transplantation Failure.
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Academic Article
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Interruption of autocrine/paracrine growth factor stimulatory mechanisms
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Academic Article
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Growth factor inhibitory molecules
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Academic Article
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Describing a transcription factor dependent regulation of the micro RNA transcriptome
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Academic Article
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At High Levels, Constitutively Activated STAT3 Induces Apoptosis of Chronic Lymphocytic Leukemia Cells.
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Academic Article
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Describing a Transcription Factor Dependent Regulation of the MicroRNA Transcriptome.
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Academic Article
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Constitutive Phosphorylation of STAT3 by the CK2-BLNK-CD5 Complex.
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Academic Article
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Factors associated with risk of central nervous system relapse in patients with non-core binding factor acute myeloid leukemia.
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Academic Article
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Activation of the B-cell receptor successively activates NF-?B and STAT3 in chronic lymphocytic leukemia cells.
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Academic Article
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Ibrutinib modulates the immunosuppressive CLL microenvironment through STAT3-mediated suppression of regulatory B-cell function and inhibition of the PD-1/PD-L1 pathway.
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Academic Article
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MYC protein expression is an important prognostic factor in acute myeloid leukemia.
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Academic Article
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Phase I study of ruxolitinib in previously treated patients with low or intermediate-1 risk myelodysplastic syndrome with evidence of NF-kB activation.
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Academic Article
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Addition of eltrombopag to immunosuppressive therapy in patients with newly diagnosed aplastic anemia.
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Concept
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Placenta Growth Factor
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Academic Article
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STAT3-Induced Wnt5a Provides Chronic Lymphocytic Leukemia Cells with Survival Advantage.
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Academic Article
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miR-543 regulates the epigenetic landscape of myelofibrosis by targeting TET1 and TET2.
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Academic Article
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STAT3 Activates the Pentraxin 3 Gene in Chronic Lymphocytic Leukemia Cells.
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Academic Article
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GLI1 activates pro-fibrotic pathways in myelofibrosis fibrocytes.
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